Software as a service (SAAS) services featuring software for modeling, rating, scoring and reporting on the conducting of simulations and predictions of properties of drugs or chemicals or vaccines including absorption, release rate, bioavailability, pharmacokinetics and pharmacodynamics, safety, toxicology, and efficacy profiles, routes of administration, and dose optimization; Software as a service (SAAS) services featuring software that allows for the simulation, prediction, rating, scoring, and reporting of drug-to-drug interactions; Software as a service (SAAS) services featuring software for the simulation, prediction, rating, scoring, and reporting of drug or vaccines or chemical effects on animals and virtual animal or patient populations; Software as a service (SAAS) services featuring software which allows researchers to adjust pharmacodynamic models to observed data and to then use the resulting fitted models to simulate, predict, rate, score, and report on pharmacodynamic changes due to changes in routes of administration, dose, dosage form, and dosing regimen of a drug or chemical or vaccine; Software as a service (SAAS) services featuring software which allow for the prediction, rating, scoring, and reporting of absorption and systemic distribution/elimination for large molecules; Software as a service (SAAS) services featuring software that incorporates artificial intelligence and machine learning to simulate, predict, rate, score, and report on the clinical efficacy of new drugs or chemicals or or vaccines before human trials and accelerate pharmaceutical drug or vaccine development and regulatory approval