Medical instruments and systems comprised of decontamination devices such as a vial, a bag, a bottle, a syringe, an infusion line, a connector, a filter, a manifold, a container port, a bag port, a bottle port, a vial port used to decontaminate surfaces of various medical devices and containers; medical instruments and systems comprised of decontamination devices such as a vial, a bag, a bottle, a syringe, an infusion line, a connector, a filter, a manifold, a container port, a bag port, a bottle port, a vial port for pharmacy use in hospitals, namely, decontamination of connections between medical devices and containers; medical instruments and systems comprised of decontamination devices such as a vial, a bag, a bottle, a syringe, an infusion line, a connector, a filter, a manifold, a container port, a bag port, a bottle port, a vial port to displace air-particles while forming a hermetically sealed connection between medical devices; medical interfaces used with medical devices to allow for hermetically sealed connection between medical devices while maintaining sterility; medical instruments and systems comprised of decontamination devices such as a vial, a bag, a bottle, a syringe, an infusion line, a connector, a filter, a manifold, a container port, a bag port, a bottle port, a vial port that securely engage one another forming a hermetically sealed connection while maintaining sterility and removing air particles; medical instruments and systems comprised of decontamination devices such as a vial, a bag, a bottle, a syringe, an infusion line, a connector, a filter, a manifold, a container port, a bag port, a bottle port, a vial port that externally displace, internally displace, slide, and reseal while maintaining a hermetically sealed connection while maintaining sterility and removing air particles