Pharmaceutical preparations adapted for the topical, injectable, and intravenous treatment of the following, cancer, increasing activity of macrophages; reduction of swelling in the brain of person suffering brain trauma; herpes, canker sores, shingles; renal failure, cardiac insufficiency, hypertension, oedema; infection, acne, mononucleosis; transplants; inflammation, elimination of tumor breakdown material (toxins and debris), decreasing side effects, relief of pain; detoxification, brochodilation; vascular ischemia; HIV(AIDS); diabetes; post-menopause; prevention of topical infection; reduction of swelling; hypertension, cardiac insufficiency; prostaglandin synthesis inhibition; enhancement of oxygenation of tissue by perfusion fluid bathing of the tissue (for transplantation purposes); sub-retinal neovascularization and as an adjunct to the treatment of cancer to prevent metastasis; arthritis or pannus; cancer tumors; inhibiting angiogenesis; controlling angiogenesis; regressing angiogenesis; basal cell carcinoma; actinic keratoses; liver spots; squamous cell tumors; metastatic cancer of the breast to the skin; primary and metastatic melanoma of the skin; malignancies and/or tumor of the skin; genital warts (condyloma acuminata); cervical cancer; human papilloma virus (HVP); psoriasis, corns on the feet; and hair loss on the heads of pregnant women; topical treatment of pain in the skin and or exposed tissue; clearing of atherosclerosis; prevention of arterial restenosis after balloon angioplasty; macrophage infiltration; pharmaceutical preparations comprising hyaluronan; licensing of intellectual property technology and research and developing for others, regarding pharmaceutical preparations, including pharmaceutical preparations comprising hyaluronan, adapted for the topical, injectable, and intravenous treatment of medical conditions and disease in humans