Providing computer software application services across a distributed network, namely, software as a service (SAAS) services featuring clinical trial data collection and monitoring services; providing computer software application services across a distributed network, namely, application service provider (ASP) services featuring database-driven software for use in clinical trial data collection and monitoring; computer services, namely, providing a web-based system and online portal for customers to remotely manage, administer, modify and control their end user computer devices, data and software applications; application service provider featuring software for providing an on-line database in the field of transaction processing to upload transactional data, provide statistical analysis, and produce notifications and reports; computer service, namely, acting as an application service provider in the field of knowledge management to host computer application software for creating, searching and retrieving information from databases and computer networks; computer service, namely, acting as an application service provider in the field of knowledge management to host computer application software for the collection, editing, organizing, modifying, book marking, transmission, storage and sharing of data and information; computer software development services in the field of software as a service; computer service, namely, acting as a software-as-a-service provider featuring database-driven collection and monitoring in the field of clinical data acquisition; application service provider (ASP), namely, hosting computer software applications of others; application service provider, namely, providing, hosting, managing, developing, researching, analyzing, reporting, and maintaining applications, software, web sites, and databases of others in the field of clinical data acquisition; application service provider, namely, hosting and managing computer software applications of independent software vendors in an effort to enable them to port their applications to a software-as-a-service environment