Describing pharmaceutical preparations for administration via respiratory airways, namely nucleotide sequences for medical use or Respiratory Anti-Sense OligoNucleotides (RASON), including aerosolized oligonucleotide preparations for the treatment of human and non-human animal respiratory, immune, endocrine, cardiovascular, neoplastic and central nervous ailments, including bronchoconstriction, difficult breathing, impeded and obstructed lung airways, allergy(ies) and/or inflammation, particularly testing, preventing and therapeutically treating respiratory, airway and pulmonary diseases and conditions, such as asthma, pulmonary vasoconstriction, inflammation, allergies, impeded respiration, Acute Respiratory Distress Syndrome (ARDS), renal damage and failure, ischemia, administration of certain drugs, including adenosine and other drugs for, for example, treating SupraVentricular Tachycardia (SVT), adenosine stress tests, infantile Respiratory Distress Syndrome (infantile RDS), pain, cystic fibrosis, allergic rhinitis, allergic bronchitis, pulmonary hypertension, pulmonary vasoconstriction, emphysema, chronic obstructive pulmonary disease (COPD), as well as cancers including leukemias, lymphomas, carcinomas, and the like, eg colon cancer, breast cancer, lung cancer, pancreatic cancer, hepatocellular carcinoma, kidney cancer, melanoma, etc, as well as all metastatic cancers, eg cancers which metastasized to the lung(s), breast, liver and prostate included